Endocrine Abstracts

Vitamin D has a role in the pathogenesis of thyroid autoimmunity.There is evidence in humans that serum levels of 1,25(OH) D3 were found to be significantly lower in patients with autoimmune thyroid diseases.We have evaluated all samples performed in the endocrine labs tested for vitamin D, AbTg, Ab-TPO and TSH from 2006 to 2015; 29216 samples for vitamin D and 41014 for TSH, AbTg and TPO were considered.We s...

Some authors observed lower thyroid antibodies titers (AbT) in children than in the adult population. The aim of this work was to consider the prevalence of positive results in AbT and elevated TSH levels. We have considered AbT and TSH measurements in a large population. We divided samples in 7 age groups 0–18, 18–20, 20–40, 40–50, 50–60, 60–70 and >70 years old. Cut-off positivity for AbTg and AbTPO was 50 and for TSH was 10 mUI/ml.<p cl...

Autoimmune Thyroid Disease (ATD) is associated with normal thyroid function (type 1) in most cases with variable incidence of functional evolution toward either hypo (type2, A or B if present or not goiter) or hyperthyroidism (type3).To study the evolution of thyroid function in a longitudinal study, along a scale of six years, in relationship to thyroid volume, 128 subjects (80 females and 48 males), aged from 28 to 78 years, were considered, with the f...

Pituitary antibodies have been measured mainly to identify patients whose disease is caused or sustained by pituitary-specific autoimmunity. Although reported in over 100 publications, this antibody test has variable results and limited clinical utility. Our goals were to: identify major sources of variability; test them experimentally for establishing an optimized immunofluorescence protocol; assess prevalence and significance of pituitary antibodies in patients with pituitar...